Shift in the paradigm of cancer treatmentDevelopment of small molecules and biologics based on Tumor associated
macrophage (TAM) in vitro diagnostics / companion diagnostics.
Core Items
First,
Next-generation immuno-metabolic anti-cancer durg that responds to the immune evasion of cancer
Second,
Development of companion diagnostic technology essential for successful anti-cancer drug development
Next-generated target for anti-cancer strategy : TAM (tumor-associated Macrophage)
Tumor-associated macrophages support cancer survival in the tumor microenvironment
Tumor-associated macrophages may be key players in the limitation of immunotherapies regulating CD8+ T cells